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Table 2 Comparative analyses of high energy phosphate levels in younger and older adults prior to and following creatine supplementation

From: The effects of age on skeletal muscle and the phosphocreatine energy system: can creatine supplementation help older adults

Variable

Young baseline†‡

Old baseline†‡

Significance

Theoretical results in young following supplementation

Theoretical results in old following supplementation

Potential statistical impact

TCr

124.6 ± 2.7

129.8 ± 4.0

< 0.001§

151.6 ± 2.7

149.1 ± 4.1

0.005 *

PCr

78.2 ± 2.3

78.4 ± 4.1

0.66

88.6 ± 2.3

84.8 ± 4.2

< 0.001 *

Cr

46.0 ± 2.3

51.4 ± 3.8

< 0.001§

64.1 ± 2.3

65.8 ± 3.9

0.03 *

ATP

24.0 ± 0.6

20.0 ± 0.6

< 0.001§

25.0 ± 0.61

21.4 ± 0.61

< 0.001 *

  1. Baseline and theoretical values are presented as mean ± pooled S.E. values and were derived from Table 1.
  2. TCr = Total creatine
  3. PCr = Phosphocreatine
  4. Cr = Creatine
  5. ATP = Adenosine triphosphate
  6. † Younger participants were between the ages of 18-36 years old, whereas older participants were between the ages of 52-79 years old.
  7. ‡ All of the referenced interventions supplemented subjects either through a loading phase (i.e., 20 g/d for 5 days) or through a 14-to-24 week supplementation protocol using 5 g/d.
  8. §= Significant difference between young and old, p < 0.05.
  9. * = Signifies a theoretical significant difference between young and old, p < 0.05.