Modelling the lactate response to short-term all out exercise

Dynamic Medicine

Table 1 3-parameter vs. 4-parameter model to describe the BLC-response to MSE10

No	Model	R²	SS ((mmol l^-1)²)	A & A₁ (mmol l^-1)	k₁ & y₁(min^-1)	A₂ (mmol l^-1)	k₂ & y₂(min^-1)	F-test
1	3-Par.	0.9612	1.4722	7.6001	0.4648		0.0665	#
	4-Par.	0.9814	0.4127	6.3018	0.3685	-18.4300	0.0206
2	3-Par.	0.9882	0.5224	7.4582	0.4197		0.0491	#
	4-Par.	0.9902	0.2586	6.3885	0.5273	-665.7111	0.0003
3	3-Par.	0.9932	0.7271	11.1438	0.5304		0.0317	#
	4-Par.	0.9975	0.1277	9.0771	0.4665	-403.1144	0.0007
4	3-Par.	0.9900	0.1645	4.3546	0.6661		0.0318	#
	4-Par.	0.9885	0.0833	3.5289	0.6283	-272.6364	0.0004
5	3-Par.	0.9934	0.6322	11.2838	0.7024		0.0498	#
	4-Par.	0.9967	0.1685	8.5908	0.6356	-21.6096	0.0209
6	3-Par.	0.9903	0.7606	9.4807	0.7199		0.0363	#
	4-Par.	0.9924	0.2987	7.3507	0.7579	-1067.4220	0.0002
7	3-Par.	0.9914	0.8179	10.4780	0.6771		0.0317	#
	4-Par.	0.9935	0.2906	8.0916	0.6162	-961.1428	0.0003
8	3-Par.	0.9805	1.0944	8.1816	0.7267		0.0348	#
	4-Par.	0.9871	0.3348	6.1414	0.6068	-917.7335	0.0002
9	3-Par.	0.9871	0.7901	8.4675	0.7458		0.0425	#
	4-Par.	0.9905	0.3065	6.4371	0.8290	-669.8416	0.0003
10	3-Par.	0.9778	2.0009	10.7703	0.5843		0.0423	#
	4-Par.	0.9928	0.3211	8.3454	0.4849	-838.0681	0.0004
11	3-Par.	0.9877	1.0402	10.6474	0.4781		0.0464	#
	4-Par.	0.9945	0.2487	8.5783	0.4454	-366.2962	0.0009

R²: coefficient of determination; SS: sum of squared residuals; A: extra-vascular increase of lactate (3-parameter model); A₁: amplitude of the invasion of lactate into the blood compartment (4-parameter model); k₁ or y₁: rate constant of lactate invasion into the blood compartment; A₂: amplitude of the evasion of lactate out of the blood compartment (4-parameter model); k₂ or y₂: rate constant of lactate evasion out of the blood compartment; #: significantly improved goodness of the fit using the 4-parameter model